Study shows the relationship between people with asthma and Diabetes, heart risk
March 21, 2011-Asthma may increase the risk of developing diabetes and heart disease, shows new research presented at the annual meeting of the American Academy of allergy, asthma and Immunology in San Francisco &.
The common denominator among these conditions seems to be inflammation, according to researchers led by John j. young, MD, MPH, of the Mayo Clinic in Rochester, n.y.
John and colleagues followed 2392 people with asthma and 4.784 people without asthma from 1964 to 1983. People with asthma are at greater risk of developing diabetes and heart disease, inflammatory bowel disease or rheumatoid arthritis, the study showed.
Specifically, the rate of diabetes in people without asthma was 104 by 100000 people compared to 138.4 by 100000 people among those with asthma. For heart disease, the rate of those without asthma was 134 by 100000 people vs. 188.6 per 100000 among participants with asthma.
"While" it is important for clinicians to know the increased risks of coronary artery disease and diabetes in asthmatics, these results should be interpreted with caution, given the preliminary nature, John says in a statement. "Given the significant people affected by asthma, we need to continue to monitor carefully the potential impact of asthma epidemiology on epidemiology of other chronic diseases."
"There is plenty of literature linking the prevalence of diabetes and chronic obstructive pulmonary disease [COPD]," says Neil Schachter, MD, professor of pulmonary medicine, Mount Sinai School of medicine in New York City. COPD is a general term for a group of progressive lung disease including emphysema and chronic bronchitis that make it more difficult to breathe.
A link between asthma and diabetes is "plausible", he says.
"The link with COPD and diabetes is supported by a link between smoking and diabetes and a theoretical link between the concept that an underlying systemic inflammation leads to COPD and diabetes," he says.
Moreover, "the extensive use of corticosteroids in COPD can unmask early or unsuspected diabetes," he says.
These factors may also play a role in asthma-diabetes link proposal, he says, adding that the rate of smoking among people with asthma is greater than one would anticipate.
"There is a link between obesity and asthma, and certainly a link between obesity and type 2 diabetes," he says.
Schachter "more epidemiological data are required before you consider this a strong association", says.
Jerome v. Tolbert, MD, PhD, Director of outreach Friedman Diabetes Institute of Beth Israel Medical Center in New York, says that the new link makes sense.
While Tolbert says I see conclusions reproduced in larger studies of populations more diverse, it says "we know that diseases such as diabetes are pro-inflammatory diseases and see these links between diabetes and autoimmune diseases."
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